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Evidences have shown that lncRNAs involve in the initiation and progression of various cancers including esophageal squamous cell carcinoma ESCC. Silencing of MALAT1 expression inhibited cell proliferation, migration and tumor sphere formation, while increasing cell apoptosis of esophageal cancer in vitro. Esophageal cancer EC is one kind of the most frequently invasive malignancies and ranks as the sixth cancer-related mortality in worldwide [ 1 ]. Here, an urgent problem is how to provide more effective therapeutic strategies to treat the patients with ESCC. More and more evidences have shown that the long noncoding RNAs lncRNAs are multiple biomarkers for predicting cancer in recent years [ 2 ]. Exploring the aberrant expression of the lncRNAs contributes to a better understanding of the molecular events and offers insight into potential molecular targets for diagnosis and therapy in ESCC [ 3 ]. Increasing evidences have shown that the aberrant expression of MALAT1 plays a crucial role in cancinogenesis [ 5 ].
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China formally kicked off its mass celebrations of 60 years of communist rule with a gun salute that rung out across Beijing's historic Tiananmen Square earlier today. Hundreds of thousands of participants marched past Tiananmen Square in costume or uniform, with floats and dancers mingling with soldiers and military hardware. Collected here are photographs of the once-in-a-decade National Day parade in Beijing, and of others commemorating the anniversary elsewhere. Kco desde Chile. That just sounds funny.
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